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The effects of iron deficiency in tissues and reduced activity of iron-containing enzymes, such as growth retardation, abnormal behavior, and physical deficiency, can therefore be gradually corrected after active iron supplementation in iron-deficient animals, in addition to accelerating hemoglobin synthesis

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A cross-sectional study of 700 community-living, physically disabled women over the age of 65 found that vitamin B 12 -deficient women were twice as likely to be severely depressed as non-deficient women (97)